CB-1 receptor – A cannabinoid receptor located primarily in the central and peripheral nervous system. The cannabinoid THC has been shown to possess a very high binding affinity with CB1 receptors. That is why consumption of cannabis strains and plants containing a high amount of THC result in a relatively potent effect, giving patients significant relief from pain, nausea, or depression.
CB-2 receptor – A cannabinoid receptor located predominantly in the immune system but also in the brain, peripheral nervous system, and gastrointestinal tract. CBD has affinity to CB-2 receptors